Acute limb ischemia means (ALI) occurs when there is a sudden lack of blood flow to a limb. Acute limb ischemia is caused by embolism or thrombosis. Thrombosis is usually caused by peripheral vascular disease (atherosclerotic disease that leads to blood vessel blockage), while an embolism is usually of cardiac origin. With proper intervention, acute limb ischemia is a highly treatable condition; however, delayed treatment (beyond 6 to 12 hours) can result in permanent disability, amputation, and/or death. Therefore, timely and correctly treatment of this disease is important.